Cisco · Identity Services Engine
CVE-2025-20281
Cisco ISE API Unauthenticated Remote Code Execution Vulnerability
What it is
A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability.
This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device.
CISA: Cisco Identity Services Engine contains an injection vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC due to insufficient validation of user-supplied input allowing an attacker to exploit this vulnerability by submitting a crafted API request. Successful exploitation could allow an attacker to perform remote code execution and obtaining root privileges on an affected device.
What to do
Apply mitigations per vendor instructions, follow applicable BOD 22-01 guidance for cloud services, or discontinue use of the product if mitigations are unavailable.
Deadline for US federal agencies: August 18, 2025
More exploited flaws from Cisco
| Added | Vulnerability | Product | Severity | Attack chance |
|---|---|---|---|---|
| Sep 16, 2026 | Incorrect Use of Privileged APIs | Identity Services Engine | Critical 10.0 | 76% |
| Jul 28, 2025 | Injection | Identity Services Engine | Critical 10.0 | 74% |
| Oct 14, 2026 | Relative Path Traversal | Secure Email Gateway | Critical 9.8 | 2.2% |
| Sep 30, 2026 | Hex Encoding | Catalyst SD-WAN Manager | Critical 9.8 | 39% |
| Sep 14, 2026 | SQL Injection | Secure Email Gateway | Critical 9.8 | 30% |
| Sep 9, 2026 | Firewall Management Center Authentication Bypass Using an Alternate Path or Channel | Secure Firewall Management Center (FMC) and Security Cloud Control (SCC) Firewall Management | Critical 10.0 | 88% |
| Aug 11, 2026 | Secure Firewall Adaptive Security Appliance (ASA) and Secure Firewall Threat Defense (FTD) Heap Inspection | Secure Firewall Adaptive Security Appliance (ASA) and Secure Firewall Threat Defense (FTD) | High 8.6 | 1.0% |
| Jul 29, 2026 | Secure Firewall Management Center Use of Hard-coded Password | Secure Firewall Management Center (FMC) | Medium 5.3 | 35% |
Sources: Known Exploited Vulnerabilities (CISA, public domain), CVE records (cve.org) and EPSS (FIRST). The chance of attacks is the EPSS estimate that someone will try to exploit the flaw in the next 30 days.