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F5 · BIG-IP

CVE-2025-53521

BigIP APM Vulnerability

Exploited in attacks Critical 9.3 Attack chance: 2.3%
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What it is

When a BIG-IP APM access policy is configured on a virtual server, specific malicious traffic can lead to Remote Code Execution (RCE).  

Note: Software versions which have reached End of Technical Support (EoTS) are not evaluated.

CISA: F5 BIG-IP APM contains a stack-based buffer overflow vulnerability that could allow a threat actor to achieve remote code execution.

What to do

Apply mitigations per vendor instructions, follow applicable BOD 22-01 guidance for cloud services, or discontinue use of the product if mitigations are unavailable.

Deadline for US federal agencies: March 30, 2026

Added to the CISA list
March 27, 2026
Published
October 15, 2025
Severity
Critical 9.3 CVSS 4.0
Chance of attacks in the next 30 days (EPSS)
2.3% in the top 16.8% of all known vulnerabilities
Weakness
CWE-121
More details
NVD · CVE.org · CISA

More exploited flaws from F5

AddedVulnerabilityProductSeverityAttack chance
May 10, 2022Missing AuthenticationCVE-2022-1388used by ransomwareBIG-IPCritical 9.8>99.9%
Nov 3, 2021Traffic Management User Interface (TMUI) Remote Code ExecutionCVE-2020-5902used by ransomwareBIG-IPCritical 9.8>99.9%
Sep 22, 2026Heap-based Buffer OverflowCVE-2026-94127BIG-IP APMCritical 9.325%
Oct 31, 2023Authentication BypassCVE-2023-46747used by ransomwareBIG-IP Configuration UtilityCritical 9.897%
Oct 31, 2023SQL InjectionCVE-2023-46748BIG-IP Configuration UtilityHigh 8.84.2%
Jan 18, 2022Buffer OverflowCVE-2021-22991BIG-IP Traffic Management MicrokernelCritical 9.862%
Nov 3, 2021iControl REST Remote Code ExecutionCVE-2021-22986used by ransomwareBIG-IP and BIG-IQ Centralized ManagementCritical 9.899.9%

All of them →

Sources: Known Exploited Vulnerabilities (CISA, public domain), CVE records (cve.org) and EPSS (FIRST). The chance of attacks is the EPSS estimate that someone will try to exploit the flaw in the next 30 days.